Ibicuruzwa
2,4-Diamino-6-HydroxyMidiDine; CYA No: 56-06-4
Synonyme: 4 (1h) -ppidinone, 2,6-DIAMINO- . 2,6-Diamino-4-hydroxypididite; 2,6-DYRIMINInol; 44914; NSC 680818; NSC9302;
Imiti yimiti ya 2,4-diamino-6-hydroxymirididididididine
● Kugaragara / ibara: bikomeye
Umuvuduko ukabije: 0.00232mhg kuri 25 ° C.
Gushonga Ingingo: 285-286 ° C (Ukuboza.) (Lit.)
Indangagaciro irohereza: 1.7990 (Ikigereranyo)
Ingingo itetse: 288.5 ° C kuri 760 mmhg
● PKA: 10.61 ± 0.50 (byahanuwe)
Flash Ingingo: 128.3 ° C.
● Zab: 98.05000
● Ubucucike: 1.84 g / cm3
● LogP: 0.50900
● Ububiko Temp.:Nate kuri + 4 ° C.
.:UMVA
.:DMOLT.:DMSO (gato), methanol (gato)
Amakuru ya hefy
● Pictogram (s):
Xi
Kode ya Hazard: xi
Imvugo: 36/37/38
● Amagambo y'umutekano: 22-24 / 25-36-26
Ingirakamaro
Ibisobanuro: 2,4-Diamino-6-HydroxyMidiDine (Dahp) ni uguhitamo, inkubi y'umuyaga ya gtp na synthesis de synthesis. Mu kagari ka huvec, IC50 yo kubuza BH4 biosynthesis ari hafi 0.3. Dahp irashobora gukoreshwa muguhagarika neza nta umusaruro muburyo bwinshi.
Gukoresha: 2,4-Diamino-6-HydroxyMidiDine (Dahp) ni uguhitamo, inkubi y'umuyaga ya gtp Mu kagari ka huvec, IC50 yo kubuza BH4 biosynthesis ari hafi 0.3. Dahp irashobora gukoreshwa muguhagarika neza nta musaruro muburyo bwinshi. [Cayman Chimical] Itangirana na Carcade ya Aromal muri synthesis.
2,4-Diamino-6-Hydroxypididite ni igikoma cya chimique hamwe na formulaire ya molecular c4h6n4o. Bikunze gukoreshwa nkabashyira hagati muri synthesi yibiyobyabwenge bitandukanye, birimo imiti ya farumasi na dyes.Ibigo bifite imiterere yimpeta ya amino igizwe nitsinda rya amino rigizwe na atome zitandukanye za karubone. Iyi miterere ituma ihuriro ryubaka ryubaka kuri synthesis ya molekile zigoye cyane Ifite porogaramu nyinshi mu nganda za farumasi, cyane cyane muri synthesis y'ibiyobyabwenge na antibiyorique.
Intangiriro irambuye
2,4-Diamino-6-Hydroxypididite ni igikoma cya chimique hamwe na formulaire ya molecular c4h6n4o. Nibigo kamaba yumuryango wa Pymuridine. Ikigo gifite imiterere yimpeta ya Pymidine, amatsinda abiri ya amino (nh2) ahujwe na 2-standes, hamwe nitsinda rya hydroxyl (OH) rihujwe kumwanya wa 6. Imiterere yimiti irashobora kugaragazwa nka: Ammonia | | H - c - c - c - n - c - c - nh2 | | OH 2,4-Diamino-6-HydroxyMidididite ifite porogaramu zinyuranye mu nganda za farumasi. Nibyingenzi muri synthesis yibiyobyabwenge byinshi, harimo ibiyobyabwenge bya antitiral na antitu. Irakoreshwa kandi mu gutanga ikigereranyo kinini cyucleotide gikoreshwa mubushakashatsi bwa farumasi.
Usibye ibyifuzo bya farumasi, 2,4-Diamino-6-HydroxyMididine nayo ikoreshwa nkikintu cyingenzi muri agrochemical. Ni ikintu cyingenzi muri synthesis cyabashinzwe gukura kwiminyuka na fungiside. Ni ngombwa cyane gukurikiza protocole ikwiye iyo ukoresheje 2,4-diamino-6-hydroxymirididididine. Kubera ko ishyirwa mu byishimo nk'izaraba, bigomba gukemurwa no kwitabwaho no kubihaha bihagije bigomba kwambara kugirango birinde guhura.
Muri make, 2,4-Diamino-6-HydroxyMidiDine ni ingingo ngengabuzima hamwe nibisabwa mubutaka nubuhinzi. Imiterere yayo ya shimi ituma ingirakamaro nkumuryango wa synthesis ya faruceticals hamwe nibihingwa bikura bitera.
