Ibicuruzwa
2,4-Diamino-6-hydroxypyrimidine 2,6-Diamino-4-Hydroxyprimidine
Synonyme: 4 (1H) -Pyrimidinone, 2,6-diamino- (8CI, 9CI); 2,4-Diamino-6-hydroxypyrimidine; 2,4-Diamino-6-pyrimidinone; 2,6-Diamino-3,4 -dihydropyrimidin-4-imwe; 2,6-Diamino-4 (1H) -pyrimidinone; 2,6-Diamino-4 (3H) -pyrimidinone; 2,6-Diamino-4-hydroxypyrimidine; 2,6-Diamino-4 -pyrimidinol; 2,6-Diaminopyrimidin-4-imwe; 2,6-Diaminopyrimidine-4 (3H) -one; 6-Aminoisocytosine; 6-Hydroxy-2,4-pyrimidinediamine; NSC 44914; NSC 680818; NSC9302;
Umutungo wimiti wa 2,4-Diamino-6-hydroxypyrimidine
Kugaragara / Ibara: bikomeye byera
Pressure Umuvuduko wumwuka: 0.00232mmHg kuri 25 ° C.
Point Gushonga Ingingo: 285-286 ° C (dec.) (Lit.)
Index Indanganturo: 1.7990 (igereranya)
Point Ingingo yo guteka: 288.5 ° C kuri 760 mmHg
● PKA: 10.61 ± 0.50 (Biteganijwe)
Point Ingingo ya Flash: 128.3 ° C.
● PSA ： 98.05000
Ens Ubucucike: 1.84 g / cm3
● LogP: 0.50900
Temp Ububiko bwububiko.: Sobanura kuri + 4 ° C.
● Yumva neza.: Umucyo
Ububasha.:DMSO (Buhoro), Methanol (Buhoro)
Isuku / Ubwiza
99% * amakuru yatanzwe nabatanga isoko
2,4-Diamino-6-hydroxypyrimidine * amakuru yatanzwe nabatanga reagent
Amakuru Yizewe
● Pictogram (s):
Xi
Odes Kode ya Hazard: Xi
Itangazo: 36/37/38
Statement Ibisobanuro byumutekano: 22-24 / 25-36-26
Amadosiye ya MSDS
Ni ingirakamaro
Ibisobanuro: 2,4-Diamino-6-hydroxypyrimidine (DAHP) ni ihitamo, ryihariye rya GTP cyclohydrolase I, igipimo kigabanya intambwe ya de novo pterin synthesis.Muri selile HUVEC, IC50 yo kubuza BH4 biosynthesis ni 0.3 mM.DAHP irashobora gukoreshwa muguhagarika neza NTA musaruro muburyo butandukanye.
Gukoresha: 2,4-Diamino-6-hydroxypyrimidine (DAHP) ni ihitamo, ryihariye rya GTP cyclohydrolase ya I, igipimo kigabanya intambwe ya de novo pterin synthesis.Muri selile HUVEC, IC50 yo kubuza BH4 biosynthesis ni 0.3 mM.DAHP irashobora gukoreshwa kugirango ihagarike neza NTA musaruro muburyo butandukanye bwakagari. 2,4-Diamino-6-hydroxypyrimidine (cas # 56-06-4) nuruvange rufite akamaro muri synthesis organique.
2,4-Diamino-6-hydroxypyrimidine ni imiti ivanze na molekile ya C4H6N4O.Bikunze gukoreshwa nkigihe gito muguhuza ibice bitandukanye, harimo imiti yimiti n amarangi.Ikigo gifite imiterere yimpeta ya pyrimidine igizwe nitsinda rya amino abiri (NH2) nitsinda rimwe rya hydroxyl (OH) ryometse kuri atome zitandukanye za karubone.Iyi miterere ituma inyubako zinyuranye zigizwe na synthesis ya molekile zigoye cyane.2,4-Diamino-6-hydroxypyrimidine irashobora kuboneka muburyo butandukanye bwogukora, harimo na cyanamide hamwe na urea.Ifite porogaramu nyinshi mu nganda zimiti, cyane cyane muguhuza imiti igabanya ubukana na antibiotike.Muri rusange, 2,4-Diamino-6-hydroxypyrimidine ni uruganda rukomeye rusanga akamaro mubikorwa bitandukanye bya chimique na farumasi.
