Ibicuruzwa
Di-tert-Butyl dicarbonate; CA No: 24424-99-9
Synonyme: Bis (Tert-BunoxycarbonyBonyL) oxide; boc (2) o cpd; dicthic; di-teyl pyrocarbonate; di-tettldarbonate
Imiti yimiti ya di-tert-Butyl dicarbonate
● Kugaragara / ibara: cyera kugeza kuri microcrystalline ifu
Umuvuduko ukabije: 0.7mmhg kuri 25 ° C.
Gushonga Ingingo: 22-24 ° C.
Indangagaciro irohereza: 1.4090
Ingingo yo guteka: 235.8 ° C kuri 760 mmhg
Flash Ingingo: 103.7 ° C.
● Zab:61.83000
● Ubucucike: 1.054 G / CM3
Ikirangantego: 2.87320
● Ububiko Temp.:2-8 uzi
.
● Amazi yoroheje .:Mabable na Decline, Toluene, Tetraydroloride, Tetraydrofuran, Dioxane, Look, Lotonitrile na Dimetitrile
● Xlogp3: 2.7
● Hydrogen Bond Abaterankunga kubara: 0
● Hydrogen Bond Kubara: 5
● Intebe ya Rotable Kubara: 6
● Misa nyayo: 218.11542367
Atom Atom Arem: 15
● Ingorabahizi: 218
Amakuru ya hefy
● Pictogram (s):
T, t +,
F, f +,
Xi
Code ya Hazard: t +, t, f, xi, f +
Amagambo: 11-19-26-36 / 37/18-40
● Amagambo y'umutekano: 16-26-28-36 / 37-45-7 / 9-37 / 39-24-36 / 37/2-33
Ingirakamaro
Amasomo ya Chimique:Andi masomo -> esters, ibindi
Inseko ya kanonical:CC (c) (c) OC (= O) OC (= O) OC (C) (c) c
Ikoresha:Di-tey-Butyl Dicarbonate (boc2o) ni regent ikoreshwa cyane yo kumenyekanisha amatsinda arengera muri synthesis ya peptide. Ifite uruhare runini mugutegura 6-acetyl - 1,2,3,4-tetrahydropyridididididine ufatanije na 2-Pipelidone. Ikora nk'itsinda rirengera rikoreshwa muri Synthesiste ya Peptide Peptide.
Intangiriro irambuye
Di-tert-Butyl dicarbonateni reagent ikoreshwa muri synthesis kama. Birazwi kandi nka T-Boc Anhydride cyangwa Boc Anhydride. Bikunze gukoreshwa kurinda amatsinda yimikorere mugihe cyibitekerezo bya shimi. Di-Tert-Butyl Dicarbonate yitabiriwe na amine kugirango ikore ibikomoka ku kaga, itanga uburinzi bwigihe gito kumatsinda ya Amine. Imyitwarire yifuzwa irangiye, itsinda rya karubata rirashobora gukurwaho byoroshye no kuvurwa byoroshye na aside, ritanga imikorere yumwimerere. Iyi ni ingamba zingirakamaro zo guhitamo guhindura amatsinda yimikorere muri molekiri kama.
Gusaba
Usibye kurinda amatsinda ya Amine, di-tet-Buyl Dicarbonate ifite izindi porogaramu zitandukanye muri synthesis kama:
Kurinda Amatsinda ya Hydroxyl:Di-Tert-Butyl Dicarbonate irashobora kwitwara na alcool kugirango ikore karubone, irinda sydroxyl itsinda. Itsinda rya karubone rirashobora kuvanwaho hakoreshejwe uburyo bukwiye, ryemerera guhitamo kurindira indi tsinda rikora.
Ibisubizo bya Carbohorlation:Di-Tert-Butyl Dicarbonate irashobora gukoreshwa nkisoko ya monoxyde ya karubone mubikorwa byahagaritswe. Ikiranuka hamwe na nuclehile nka amine, alcool, na tiyoli kugirango bakore ibicuruzwa bya kaburimbo.
Gutegura chloride ya aside:Witondere di-tert-Butyl dicarbonate hamwe na thioyl chloride cyangwa oxalyl chloride itanga chloride ihuye. Abashimusi bacide ni reagetile reagentile ikoreshwa muburyo butandukanye bwo guhindura.
Synthesis-Plasse Synthesis:Di-Tert-Butyl Dicarbonate ikunze gukoreshwa mukurinda no kwiyambura ingamba zikomeye-Synthede Peptide. Ikoreshwa mukurinda aside amine mugihe cyo kwagura urunigi no gukuraho amatsinda yo kurengera gushyira ahagaragara amatsinda ya amino kugirango asubirwemo.
Imyitwarire y'agateganyo:Di-Tert-Butyl Dicarbonate irashobora gukora nkumukozi wigenga urunigi muburyo bwo kwiga. Irashobora kubyitwaramo no gukura iminyururu ya polymer, guhagarika imikurire yabo cyangwa kubyara ibibanza bishya.
Izi ni ingero nkeya za porogaramu nyinshi za di-Tert-Butyl dicarbonate muri synthesis kama. Guhinduranya no koroshya imikoreshereze bikaba byiza mu guhindura imiti itandukanye.
