Ibicuruzwa
Dl-4-chlorophenyclyclycine; CYA No 6212-33-5
Synonyme: 6212-33-5; 2-Amino-2- (4-chlorophenyl) acide; dl-chlorophenyclycine; dl-chlorophenyclcine; acino- aside; 4-chlorophenyclycine; dl- (4-chlorophenyl) glycine; (+ chplophenyclycine; mfcd acide, .LPHA.-Amino-4-chloro-; l -dl-phg (4-cl) -oh; methyln-methyln-carbamoylmaleate; rm2hw43TGA; 2- (p-chlorophenyl) glycine; dl-chlorophenyl ); 4-chloro-dl-2-phenylglycine; dl-2- (p-chlorophenyl) glycine40; (4-cl #; Bcp25773; BBL02221163; BDBM5015001500 aside; 7l-304s; AB02094; Ab15770; AB16238; AB88361; HL-CHLORO-AMOROPHEPHICTIC Aside; sy017756; Sy034115; Sy034129; AM2006079; BB 0,3 (Tlc); q-102258; F2147-0645; z37024646
Imiti yimiti ya dl-4-chlorophenyclycine
● Kugaragara / ibara: cyera kugeza ifu yumuhondo
. Umuvuduko mwinshi: 7.45e-05mhg kuri 25 ° C.
Gushonga Ingingo: 220-230 ° C.
Indangagaciro iroba: 1.603
Ingingo itetse: 328.8 ° C kuri 760 mmhg
● PKA: 1.81 ± 0.10 (byahanuwe)
Flash Ingingo: 152.7 ° C.
● Zab:63.32000
● Ubucucike: 1.392 G / CM3
● LogP: 2.12470
. Ububiko
.
● Xlogp3: -1.1
● Hydrogen Bond Abaterankunga kubara: 2
● Hydrogen Bond Kubara: 3
● Bond Kubara: 2
● Misa nyayo: 185.0243562
Atom Atom Kira: 12
Kugorana: 166
Amakuru ya hefy
● Pictogram (s):
Xn
Code ya Hazard: XN
Imvugo: 22-36 / 37/2 / 38
● Amagambo y'umutekano: 26-36
Ingirakamaro
Inseko ya kanonical:C1 = CC (= CC = C1C (C (= o) o) o) cl
Ikoresha:Nibikoresho byingenzi byingenzi kandi hagati ikoreshwa muri synthesis kama, imiti, agrochemical na dyestuff.
Intangiriro irambuye
2-Amino-2- (4-chlorophenyl) acide izwi kandi nizina ryamashusho, 4-chplo-alpha-aminobenzenetic acide. Ni ifu yera ya kirisiti ifite formulaire ya c8h8clno2 nuburemere bwa molekile ya 185.61 g / mol.
Hano haribindi bisobanuro kuri 2-amino-2- (4-chlorophenyl) acide ya acetike:
Synthesis:Iki kigo gishobora kunyurwa nuburyo butandukanye, harimo reaction ya 4-chloropacetorinononononononononononononononononononononononononononononononononononononononononononononononone igabanuke imbere yumukozi ugabanuka nka sodium borohydride, cyangwa kumyitwarire ya 4-chlorophenakl brodite na sodium glycinate.
Umubiri na shimi:
1
.
3.ph: Mu gisubizo gitangaje, iki kigo ni acide intege na ph hafi 5-6.
Ibinyabuzima:
1.Umuhemu wibintu: Nubwo hari amakuru make aboneka mubikorwa bya farmacologiya ya 2-Amino-2- (4-chlorophenyl) acide, ubushakashatsi bumwe bwerekana ko bishobora kuba bifite ibintu bishobora kurwanya imitungo na analtic.
. Ariko, biteganijwe ko bizasenyuka muburyo bworoshye no kurandura mumubiri.
Ibitekerezo by'umutekano:
1.Miui 2-Amino-2- (4-chlorophenyl) acide ya acetike ifatwa nkaho ifite uburozi buke, birasabwa kubyitondera no kwitonda no gukurikiza ingamba zumutekano zijyanye mugihe utwara cyangwa ukorana niki kigo.
2.Ni ngombwa kwambara ibikoresho birinda, nka gants na roves, no kwemeza umwuka ukwiye iyo ukorana nibi bintu.
3. Kenshimakenya kumabara yumutekano (SDS) no kugisha inama umurongo ngenderwaho numutekano bijyanye no gufata no gukoresha iki kigo.
Wibuke, amakuru yatanzwe hano ni incamake rusange kandi ntigomba gufatwa nkuburyo bwuzuye cyangwa bwuzuye. Kubisabwa cyangwa intego zihariye, burigihe birasabwa kugisha inama ibitabo byihariye cyangwa amasoko yizewe kugirango ubone ibisobanuro birambuye.
Gusaba
2-Amino-2- (4-chlorophenyl) acide ya acetike, izwi kandi nka 4-chpha-aminobenzenetic acide, ifite porogaramu zishoboka mumirima itandukanye. Hano hari porogaramu zishoboka:
Inganda za farumasi:
1.Synthesis yibiyobyabwenge: Irashobora gukoreshwa nkigituba cyangwa hagati muri synthesis yimiti yimiti nka analgesike, ibiyobyabwenge byo kurwanya ibiyobyabwenge, cyangwa abashinzwe kurwanya bagiteri.
2.Iterambere rya Prodrug: 2-Amino-2- (4-chlorophenyl) acide ya acetike irashobora gukoreshwa mugutezimbere prodrugs, zidakora cyangwa muburyo bukora ibiyobyabwenge cyangwa ibintu bifatika byibiyobyabwenge bihinduka mumubiri. Ibi birashobora gufasha kunoza imikorere yibiyobyabwenge, bioakwaiLalablity, cyangwa kugabanya ingaruka mbi.
Ubushakashatsi bwa Shimil:
1.Synthesis kama: Ibigo birashobora gukoreshwa muri laboratoire kuri synthesi yimyanya kama, cyane cyane muri synthesis yibinyabuzima bigoye.
2.Ligand Synthesis: Irashobora gukoreshwa kugirango itegure Ligands yo guhuza chimie cyangwa inamisi kuburyo butandukanye.
Inganda zubuhinzi:
1.Iterambere ryica udukoko: 2-Amino-2- (4-chlorophenyl) acide ya acetike irashobora gukoreshwa muguhindura imiti yica udukoko cyangwa imiti yimiratsi itanga neza cyangwa kugabanya ingaruka zishingiye ku bidukikije.
Ubushakashatsi n'iterambere:
1.Ubushakashatsi bwa Shimil: Iki kigo gishobora gukoreshwa nkigipimo gisanzwe cyangwa cyerekana intego yo gusesengura nuburyo bwo guteza imbere laboratoire yubushakashatsi.
2.Ubushakashatsi bwibinyabuzima: Irashobora gukoreshwa mubyigisho bikora iperereza ku ruhare rwa Amines n'ibikomoka mu nzira zitandukanye z'umubiri cyangwa ibinyabuzima.
Nyamuneka menya ko porogaramu yihariye hamwe na 2-amino-2- (4-chlorophenyl) acide ya acetike irashobora gushingira kubushakashatsi niterambere. Buri gihe ujye ugisha inama yubumenyi bwa siyansi, ibisabwa kugenzura, hamwe nabanyamwuga bakwiye mbere yo gukoresha cyangwa gusuzuma ibyifuzo byayo mumurima runaka.
