Ibicuruzwa
Mopso; CA No: 68399-77-9
Synonyme: 3-morpholino-2-hydroxypropanfonic acide; 3-morpholino-2hopsa
Imiti yimiti ya mopso
● Kugaragara / Ibara: Ifu yera
Gushonga Ingingo: 275-280 ° C (Ukuboza.)
Indangagaciro iroba: 1.539
● PKA: PK1: 6.75 (37 ° C)
● Zab:95.45000
● Ubucucike: 1.416 G / CM3
● LogP: -0.41400
SHAKA TEMP.
.:H2O: 0.5 m kuri 20 ° C, birasobanutse
. Amazi yoroheje
● Xlogp3: -4.1
● Hydrogen Bond Abaterankunga kubara: 2
● Hydrogen Bond Kubara: 6
● Intebe ya Rotable Kubara: 4
● Misa nyayo: 225.06709375
Atom Atom Kirem: 14
Kugorana: 254
Amakuru ya hefy
● Pictogram (s):
Xi
Kode ya Hazard: xi
Imvugo: 36/37/38
● Amagambo y'umutekano: 26-36-37 / 39
Ingirakamaro
Amasomo ya Chimique:Azogen Ibice -> morpholines
Inseko ya kanonical:C1CCCn1CC (CS (= O) (= o) o) o
Ikoresha:Mopso ni buffer ikora muri 6-7 ph. Ikoreshwa muri synthesis ya farumasi. Mopso ni buffer y'ibinyabuzima nayo yitwaga nk'igisekuru cya kabiri "cyiza" cyiza cyerekana ko ushimishije ugereranije n'uburasirazuba "bwiza". PKA ya mopso ni 6.9 zibigira umukandida mwiza kumashusho ya buffer asaba phi munsi ya physiologie kugirango ukomeze ibidukikije bihamye. Mopso ifatwa nkibikorwa byuburozi kumirongo ya selile kandi itanga ibisobanuro-bitangaje.Mopharmaceacediace yimico ya selile, ibishushanyo mbonera byimiti ya kilingele (byombi hejuru no hepfo no kumanura.
Intangiriro irambuye
Mopso (3- (n-morholino) aside propanekonic) ni igikoma cyimiti kiri mubyiciro bya acide sulfonic. Hano hari ingingo zingenzi zerekeye mopso:
Imiterere yimiti:Mopso ifite imiti yimiti C7H17No4s kandi igizwe nimpeta ya morfocy (compound ya heterocyccial) yometse kuri propane hamwe nitsinda rya sulfonic rifite acide sulfonic (so3h).
Buffer Ibintu:Mopso ikunze gukoreshwa nka buffer mubinyabuzima na moleculay ibinyabuzima bishingiye kuri biologiya. Ifite agaciro ka PKA igera kuri 7.20 kuri 25 ° C, bigatuma bikwiranye no kwivuza muri PH amanota 6.2 kugeza 7.6.
Ubushobozi bwa buffer:Mopso ifite ubushobozi buciriritse muri PH ya PH. Irashobora gufasha kubungabunga PH ihamye mubinyabuzima na sisitemu zitandukanye, gukumira ihindagurika rishobora kugira ingaruka kubikorwa bya enzymes cyangwa umutekano wa molekile.
Gusaba ibinyabuzima: Mopso ikoreshwa kenshi mumico ya selile, kwezwa kwa poroteyine, nibindi bitekerezo bifatika bisaba PH yihariye. Ningirakamaro cyane mubihe aho PH igomba gukomeza hafi yimiterere ya physiologique.
Umutekano Wimiti: Mopso ni imiti ihamye kandi ntabwo byoroshye gutesha agaciro imiterere isanzwe. Ariko, ni ngombwa kubibika mu bidukikije byumye kandi bikonje kugirango wirinde kwinjiza neza no gutesha agaciro.
Ibitekerezo by'umutekano:MOPSO muri rusange ifatwa nkaho ifite umutekano kugirango ikoreshwe muri laboratoire iyo ikore neza. Ariko, kimwe n'imiti iyo ari yo yose, ni ngombwa gukurikiza protocole y'umutekano ikwiye, nko kwambara ibikoresho bikwiye byo kurinda (gants, goggles) no kuyikora mu gace gahuje neza.
Birakwiye ko tumenya ko gukoresha neza hamwe na Mopso bishobora gutandukana bitewe nibisabwa mubushakashatsi. Buri gihe reba urupapuro rwamagambo ya tekinike cyangwa kugisha inama yabigize umwuga kugirango ubone amabwiriza arambuye namabwiriza yihariye.
Gusaba
Mopso ifite uburyo butandukanye mubikorwa bitandukanye bya siyansi. Dore porogaramu zimwe na zimwe za MoPso:
Umukozi wa Buffring:Mopso ikunze gukoreshwa nkumukozi wibanze mubinyabuzima nubushakashatsi bwibinyabuzima. Ifasha gukomeza ph ihoraho mubisubizo, bifite akamaro mugukomeza ibikorwa no gutuza imitunganyirize, proteyine, nibindi bilimemolecules.
Umuco w'akagari:MoPSO ikoreshwa mu bitangazamakuru by'umuco kagoshe kugira ngo akomeze PH (hafi ya PH 7.2) ibyo byiza byo gukura no kubungabunga imirongo imwe n'imwe.
Kwezwa kwa proteine:Mopso irashobora gukoreshwa nka buffer mubikorwa byo kwezwa kwa poroteyine, aho bifasha gukomeza gushikama nigikorwa cya poroteyine mugihe gikwiye.
Enzyme Inyigisho:MoPSO ikoreshwa kenshi nka buffer mubushakashatsi bwamazi bwo gukomeza ibikorwa byiza bya PH kubikorwa bya Enzyme. Ni ingirakamaro cyane mukwiga imisemburo ikora neza hafi ya PH 7.
Electrophoresis:Mopso irashobora gukoreshwa nka buffer muri tekinike ya electrophores, nka SPS (sodium dodecyl sulfate-polyacrylamide-polkacrylamide ya electrophores), kugirango itange PH yifuzwa kubitandukanya na poroteyine.
Kumenyekanisha ibiyobyabwenge:MoPSO ikoreshwa mu gushyiraho ibiyobyabwenge bimwe, cyane cyane ibisaba PH yihariye yo gutuza no gukora neza.
Synthesis cynthesis: Mopso irashobora gukoreshwa nkicyitonderwa cyangwa umusemburo mubisubizo bimwe na bimwe bya shimi na synthesis.
Ni ngombwa kumenya ko kwibanda no gukoresha mopso bishobora gutandukana bitewe nibisabwa nibisabwa mubushakashatsi. Buri gihe ujye ubaza ibitabo cyangwa ukurikize umurongo ngenderwaho watanzwe nabakora cyangwa abashakashatsi bagize uruhare mubikorwa byihariye byo kwiga.
