Ibicuruzwa
N, n'-diisopropylcarbodiimimage; cas No: 693-13-0
Synonyme: 1,3-diisopropylcarbodiimimage
Imiti yimiti ya N, n'-diisopropylcarbodiimide
● Kugaragara / Ibara: ibara ridafite ibara ryijimye
Umuvuduko ukabije: 34.9HPA kuri 55.46 ℃
● Gushonga Ingingo: 210-212 ° C (Ukuboza)
Index yerekana: N20 / D 1.433 (Lit.)
Ingingo itetse: 146.5 ° C kuri 760 mmhg
● Flash Ingingo: 33.9 ° C.
● Zab:24.72000
● Ubucucike: 0.83 G / CM3
● LogP: 1.97710
● Ububiko Temp.:2-8 uzi
.
.
● XOGP3: 2.6
● Hydrogen Bond Abaterankunga kubara: 0
● Hydrogen Bond Kubara: 2
● Bond Kubara: 2
● nyayo misa: 126.115698455
Atom Atom Kirem: 9
Kugorana: 101
Amakuru ya hefy
● Pictogram (s): t +,
T,
F
Code ya Hazard: t +, t, f, xn
Imvugo: 10-26-36 / 37/18-41-42 / 43-37 / 38
● Amagambo y'umutekano: 26-36 / 37/2-45-38-28A-16-22
Ingirakamaro
Amasomo ya Chimique:Azogen Ibice -> Ibindi bigo bya azoge
Inseko ya kanonical:CC (c) n = c = nc (c) c
Ibigeragezo bya EU ya vuba:Ingaruka ndende za aldara? 5% na
Ibisobanuro birasobanura: Dic) ni amazi meza ashobora gutangwa byoroshye nubunini. Buhoro buhoro, bwitaweho ubushuhe kuva mu kirere, bityo akabikwa igihe kirekire icupa bigomba guhuzwa hamwe n'umwuka wumye cyangwa gaze yumye kandi kashe. Ikoreshwa muri chimie ya peptide nkumuturage uhuza. Nuburozi cyane kandi bwateje umubonano dermatitis mumukozi wa laboratoire.
Ikoresha:Iki gicuruzwa gikoreshwa cyane muri amikagin, glutathione umwumva umwubaha, kimwe no muri synthesis ya aside anhydride, Aldehyde, Ketone, Isonenate; Iyo ikoreshwa nkuburaro bwumushyitsi, yitwara kuri diclyclohexyluro mukirubuga mugihe gito munsi yubushyuhe busanzwe. Iki gicuruzwa kirashobora kandi gukoreshwa muri synthesis ya peptide na aside iricleic. Biroroshye gukoresha iki gicuruzwa kugirango ubyare hamwe nibice bya Carboxy na Amino-itsinda muri peptide. Iki gicuruzwa gikoreshwa cyane mubuvuzi, ubuzima, gutora no kubinyabuzima nibinyabuzima, nizindi mirima ya synthetic. N, n'-diisopropylcarbodiedide ikoreshwa nkumutwe muri chimic organic orchic chimie. Ikora nk'imiti hagati ya chimique kandi nk'intangiriro ya sarin (intwaro ya chimique). Irakoreshwa kandi muri synthesis ya peptide na aside iricleic. Byongeye kandi, ikoreshwa nka antineoplastique kandi igira uruhare mukuvura melanoma mbi na sarcom. Usibye ibi, ikoreshwa muri synthesis ya aside anhydride, Aldehyde, Ketone na isocyanate.
Intangiriro irambuye
N, N'-diisopropylcarboDiImimage, isanzwe ihwanye na dic, ni imiti ifite imiterere ya molecular c7h14n2. Nibintu bitagira ibara bikundwa mubintu bisanzwe bisanzwe nkaba erebire na alcool. Dic ikoreshwa cyane nka synthesi ya kama kandi igira uruhare rukomeye mubisubizo bitandukanye.
Dic ikoreshwa cyane nkumukozi usanzwe muri synthesis ya peptide, niyo nzira yo kwinjira muri amine aside amine hamwe kugirango ikore peptide cyangwa poroteyine. Ikora nk'indabyongenga, yorohereza guhuza aside amine mu gukora amatsinda ya kanseri, mubisanzwe binyuze mu gushiraho umuvuduko udasanzwe witwa Ester. Iki gihe cyo gufatanya ibintu hamwe nitsinda rya Amino mbere yo gukurikiranwa no kurandura no kurandura burundu imiyoboro ya peptide.
Dic kandi ikoreshwa mubindi bitekerezo birenze synthesis ya peptide, nkubushishozi, bikabije, na Urethane Synthesis. Ikora nkumukozi umwubatsi muriyi reaction, yorohereza kuvanaho molekile y'amazi, bityo bigatwara ibintu byifuzwa imbere.
Bitewe no guhangayikishwa no gutontoma, dic bigomba gukemurwa no kwitonda. Mubisanzwe bikoreshwa muburyo bwuzuye umwotsi na gants yo kurinda igomba kwambarwa kugirango ikumire uruhu. Byongeye kandi, kimwe n'imiti iyo ari yo yose, ni ngombwa gukurikiza inzira z'umutekano zikwiye kandi ukagisha inama y'urutonde rw'umutekano wibikoresho (MSDS) kugirango ubone ibisobanuro birambuye.
Muri make, n, N'-diisopropylcarbodide ni reagent ya Versiatile ikoreshwa muri synthesis zitandukanye muburyo butandukanye, harimo na synthesis ya peptide, gushikama, na Urethane Synthesis. Uruhare rwarwo nkumukozi uhuza kandi uharanira umwuma bituma bigira igikoresho cyingenzi mumurima wa chimie kama.
Gusaba
N, n'-diisopropylcarbodiedide (dic) ifite porogaramu nyinshi muri synthesis na farumasi. Hano hari uburyo bwihariye bwo gukoresha Dic:
SynthesisDic isanzwe ikoreshwa nkumukozi usanzwe muri synthesis ikomeye-Pynthesiste kugirango ikore inkwano ya peptide hagati ya amino. Ikora amatsinda ya Carboxyl ya Medide yarinzwe amine, abakwemerera kwitwara nitsinda rya amino, bikaviramo gushinga ubumwe bwa peptide.
Kumurongo no gukomeraDic ikoreshwa nkumuntu unyurwa kugirango uteze imbere aside acide ya karbox Yorohereza gushiraho amayeko na esters mugukuraho amazi kuva imvange.
Urethane Synthesis:Dic irashobora gukoreshwa nkumukozi uhuza muri synthesis yimigabane. Ifasha reaction hagati ya isocyonates na alcool kugirango ukore Urethanes.
Ibisubizo bihuzaga na Carbodiimide:Dic ikunze gukoreshwa nkumugozi uhuza muburyo butandukanye, nka synthesis yo mu Bumuntu, iragaba, nibindi biligi bikora. Itezimbere guhuza acide ya carbox, aside acide, cyangwa acyl amine na amine, hydroxylaminanimine, nibindi tuclefile.
Impinduka za okiside:Dic irashobora gukoreshwa muburyo bwa okiside, nkibisobanuro bya oleidive ya olefins na okiside ya sulfides kuri sulfoxide cyangwa sulfone.
Ni ngombwa kumenya ko dic ari ikirere - kandi ubuhemu - bityo rero bigomba gukemurwa mu gace gahujwe neza cyangwa munsi yinzira nyayo. Byongeye kandi, ingamba z'umutekano, nka gants hamwe na Goggles, bigomba gufatwa mugihe ukorana na Dic bitewe na kamere yacyo.
