Ibicuruzwa
Fenilurea
Imiti ya Fenilureya
| Ingingo yo gushonga | 145-147 ° C (lit.) |
| Ingingo yo guteka | 238 ° C. |
| ubucucike | 1,302 g / cm3 |
| ubucucike bw'umwuka | > 1 (vs ikirere) |
| indangagaciro | 1.5769 (igereranya) |
| Fp | 238 ° C. |
| ububiko bwa temp. | Komeza ahantu hijimye, Gufunzwe byumye, Ubushyuhe bwicyumba |
| gukemura | H2O: 10 mg / mL, birasobanutse |
| pka | 13.37 ± 0.50 (Byahanuwe) |
| ifishi | Ifu, Crystal na / cyangwa Chunks |
| ibara | Umweru kugeza umuhondo |
| Amazi meza | Kubora mumazi. |
| Merk | 14,7319 |
| BRN | 1934615 |
| Igihagararo: | Ihamye.Ntibishobora kubangikanya imbaraga zikomeye za okiside. |
| InChIKey | LUBJCRLGQSPQNN-UHFFFAOYSA-N |
| CAS DataBase Reba | 64-10-8 (CAS DataBase Reba) |
| Sisitemu yo Kwiyandikisha Ibintu | Urea, fenyl- (64-10-8) |
Fenilurea Ibisobanuro
6-Amino-1,3-dimethyluracil ni imiti ivanze na molekile ya C6H9N3O.Nibintu kama kama mumuryango wa uracil.Uru ruganda rufite impeta ya uracil hamwe nitsinda rya amino (NH2) ryometse kumyanya 6 hamwe na methyl ebyiri (CH3) zifatanije na 1- na 3-imyanya.Imiterere yimiti irashobora kugaragazwa nka: biteye ubwoba ||CH3 - C - C - C - N - C - CH3 || ammonia 6-Amino-1,3-dimethyluracil ni intera muguhuza ibice bitandukanye bya farumasi.Ikoreshwa cyane mugukora imiti igabanya ubukana na antitumor.Nibikoresho byo gutangiza synthesis ya nucleoside igereranya kuvura virusi na kanseri.
Mubyongeyeho, 6-amino-1,3-dimethyluracil nayo ikoreshwa mubijyanye no kwisiga.Irashobora gukoreshwa nkibigize ubwiza nibicuruzwa byita kumuntu nka cream y'uruhu n'amavuta yo kwisiga.Imiterere yacyo ituma ikoreshwa nkibikoresho byuruhu hamwe nubushuhe.Uburyo bukwiye bwo kwirinda umutekano burasabwa mugihe ukoresha 6-amino-1,3-dimethyluracil.Bika ahantu hakonje, humye kure yumuriro cyangwa ubushyuhe.Byongeye kandi, birasabwa kwambara ibikoresho birinda umuntu nka gants na gogles kugirango wirinde guhura nuru ruganda.
Mu gusoza, 6-amino-1,3-dimethyluracil ni ifumbire mvaruganda ikoreshwa nkigihe gito muguhuza imiti yimiti, cyane cyane imiti igabanya ubukana na antitumor.Irakoreshwa kandi mumavuta yo kwisiga kumiterere yuruhu rwayo.Umutekano ugomba gukurikizwa mugihe ukemura iki kigo.
Amakuru yumutekano
| Kode ya Hazard | Xn |
| Ibisobanuro | 22 |
| Amatangazo yumutekano | 22-36 / 37-24 / 25 |
| WGK Ubudage | 3 |
| RTECS | YU0650000 |
| TSCA | Yego |
| Kode ya HS | 29242100 |
| Uburozi | LD50 umunwa mu mbeba: 2gm / kg |
Gukoresha Fenilureya Na Synthesis
| Ibikoresho bya Shimi | Urushinge rutagira ibara rumeze nka kirisiti cyangwa ifu yera.Gushonga ingingo ya 147 ° C (kubora), gushonga mumazi ashyushye, inzoga zishyushye, ether, Ethyl acetate na acide acike. |
| Gukoresha | Fenilureas ikoreshwa mubutaka bwifashishwa mu kurwanya ibyatsi n’ibyatsi bito bito bito. |
| Gukoresha | Fenil urea ikoreshwa muri synthesis organique.Ikora nka ligand ikora neza kuri palladium-catisale Heck na Suzuki reaction ya aryl bromide na iyode. |
| Kwitegura | Fenilurea ikomatanyirizwa hamwe na reaction ya aniline na urea.Shira urea, aside hydrochloric na aniline mumasafuriya ya reaction, shyushya kandi ubyereke, usubire kuri 100-104 ° C kumasaha 1, ongeramo amazi hanyuma ukangure, ukonje, ushungura, koza cake uyungurura amazi, hanyuma wumuke kugirango ubone ibicuruzwa byarangiye. ya fenylurea. |
| Gusaba | Phenyl urea yica udukoko, amazi, uburozi bigaragara nkamazi yashonze cyangwa yahagaritswe mubitwara amazi.Harimo kimwe mubintu byinshi bifitanye isano (Diuron, Fenuron, Linuron, Neburon, Siduron, Monuron) bikomoka kuri urea.Umwikorezi ni amazi yoroha.Uburozi muguhumeka, kwinjiza uruhu, cyangwa kuribwa. |
| Ibisobanuro rusange | Ikintu gikomeye cyangwa amazi yinjiye mumatwara yumye.Ifu yuzuye.Harimo kimwe mubicuruzwa byinshi bifitanye isano (Diuron, Fenuron, Linuron, Monuron, Neburon, Siduron) bikomoka kuri urea.Uburozi muguhumeka, kwinjiza uruhu, cyangwa kuribwa.Shakisha izina rya tekiniki yica udukoko twangiza kurupapuro rwoherejwe hanyuma ubaze CHEMTREC, 800-424-9300 kugirango ubone ibisobanuro. |
| Umwirondoro wa reaction | Organic amide / imide ikora hamwe na azo hamwe na diazo kugirango bibyare imyuka yubumara.Imyuka yaka ikorwa nigikorwa cya amide / imide hamwe ningingo zigabanya imbaraga.Amide nintege nke cyane (intege nke kuruta amazi).Imide ntabwo ari shingiro nyamara kandi mubyukuri reaction hamwe nifatizo zikomeye zo gukora umunyu.Ni ukuvuga, barashobora kwitwara nka acide.Kuvanga amide hamwe ningingo zangiza nka P2O5 cyangwa SOCl2 bibyara nitrile ihuye.Gutwika kw'ibi bikoresho bitanga okiside ivanze ya azote (NOx).Harimo kimwe mubintu byinshi bifitanye isano (Diuron, Fenuron, Linuron, Neburon, Siduron, Monuron) bikomoka kuri urea. |
| Ubuzima | Uburozi bukabije, bushobora guhitana abantu iyo buhumeka, kumira cyangwa kwinjizwa mu ruhu.Irinde guhuza uruhu urwo arirwo rwose.Ingaruka zo guhura cyangwa guhumeka zirashobora gutinda.Umuriro urashobora kubyara imyuka irakara, yangirika kandi / cyangwa uburozi.Amazi ava mumashanyarazi cyangwa amazi yamazi arashobora kwangirika kandi / cyangwa uburozi kandi bigatera umwanda. |
| Fire Hazard | Ntibishobora gukongoka, ibintu ubwabyo ntibitwika ariko birashobora kubora nyuma yo gushyuha kugirango bitange umwotsi wangirika kandi / cyangwa uburozi.Ibikoresho birashobora guturika iyo bishyushye.Amazi ashobora guhumanya inzira y'amazi. |
| Uburyo bwo kweza | Koresha kristu urea mumazi abira (10mL / g) cyangwa inzoga ya amyl (m 149o).Kuma mu ziko ryamazi kuri 100o.1: 1 resorcinol complex ifite m 115o (kuva EtOAc / * C6H6).[Beilstein 12 H 346, 12 II 204, 12 III 760, 12 IV 734.] |
